Andras Lakatos
Principal Investigator, Cambridge Centre for Brain Repair,
Department of Clinical Neurosciences, University of Cambridge
SpR in Clinical Neurology, Department of Neurology, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Trust
Interests:
Andras is interested in the adaptive changes in glia-neuron interactions following remote axonal insults, such as axotomy and demyelination. The particular focus is how endogenous cortical/gray matter astrocytes and stem cells responding to such cues would influence synaptic plasticity and neuronal integrity. His work involves a comparative analysis of molecules influencing synaptic maturation and neuronal survival in both animal and co-culture model systems. A more detailed understanding of these mechanisms may provide new alternative neuroprotective therapeutic targets for neurological disorders with a particular relevance to chronic demyelinating diseases, such as multiple sclerosis. He has several collaborations with Cambridge based laboratories and is also keen on progressing towards translational strategies.
People:
Andras Lakatos (Walker Fellowship, BRC)
Nike Lau (Wellcome Trust Scholarship with AL and Part II PDN)
Kerala Adams-Carr (Part II PDN)
Maria Falusi (Visiting student from the University of Szeged)
Collaborations:
Ragnhildur Thora Karadottir (electrophysiology)
Robin Franklin & Chao Zhao (transgenic models)
James Fawcett & Jessica Kwok (mol. biology of axon guidance)
Stefano Pluchino (stem cells, translational models)
Funding:
Walker Fund (AL)
Wellcome Trust (with NL)
Contact:
Dr Andras Lakatos
Centre for Brain Repair
University of Cambridge
Forvie Site, Robinson Way
Cambridge, CB2 0PY, UK
Tel: +44 (0)1223 767761
Email: AL291@cam.ac.uk