John van Geest Centre for Brain Repair

School of Clinical Medicine



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Andras Lakatos

Principal Investigator, John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge

MRC Clinician Scientist and Academic Consultant Neurologist, Department of Neurology, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Trust


Andras is interested in the adaptive changes in glia-neuron interactions following remote axonal insults, such as axotomy and demyelination. The particular focus is how endogenous cortical/gray matter astrocytes and stem cells responding to such cues would influence synaptic plasticity and neuronal integrity. His work involves a comparative analysis of molecules influencing synaptic maturation and neuronal survival in both animal and co-culture model systems. A more detailed understanding of these mechanisms may provide new alternative neuroprotective therapeutic targets for neurological disorders with a particular relevance to neurodegenerative conditions and chronic demyelinating diseases, such as multiple sclerosis. He has several collaborations with Cambridge based laboratories and is also keen on progressing towards translational strategies.



  • Andras Lakatos (Walker Fellowship, BRC)
  • Giulia Tyzack (van Geest studentship)
  • Daniel Barson (Gates MPhil student)
  • Adrian Tan (MPhil student, co-supervised with Phil Buttery)
  • Alejandro Carnicer (Part II undergraduate)

Former members

  • Nike Lau (Wellcome Trust Scholarship with AL and Part II PDN)

    Purified Astrocyte-Neuron Co-culture

  • Kerala Adams-Carr (Part II PDN)
  • Maria Falusi (Visiting student from the University of Szeged)



Ragnhildur Thora Karadottir

Robin Franklin & Chao Zhao

James Fawcett & Jessica Kwok

Phil Buttery



Walker Fund (AL)

Wellcome Trust (with NL)

van Geest fund



Dr Andras Lakatos

Centre for Brain Repair

University of Cambridge

Forvie Site, Robinson Way

Cambridge, CB2 0PY, UK

Tel: +44 (0)1223 767761


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